Physician-led aesthetics · Orlando
Regenerative aesthetics & physician-led skin rejuvenation in Orlando
Botox Cosmetic and Xeomin, Juvéderm and Restylane fillers, Radiesse and Sculptra, medical microneedling and PRP/PRF, planned and performed by Kenny Chantasi, DO, after a medical exam. Every option comes with its FDA status, including the regenerative therapies that are still investigational. No fake before-and-afters.
Scheduling opens securely in Prospyr · starts with the Aesthetic Goals Assessment
Kenny Chantasi, DOPerforms aesthetic evaluations and treatments himself · Board-certified, PM&R and Pain Medicine
In one paragraph
What “regenerative aesthetics” means at PrimeCell
Short answer
At PrimeCell, regenerative aesthetics means physician-led procedures that work with your own tissue: prompting the skin to remodel after controlled micro-injury, using a concentrate of your own platelets (PRP or PRF), or stimulating collagen gradually. In selected cases it also includes stem-cell-derived and exosome products, which are investigational: no stem cell or exosome product is FDA-approved for cosmetic use.
“Regenerative” has become one of the most stretched words in aesthetics. It gets applied to everything from serums to injectables. We use it narrowly. Every option on this page is something Dr. Chantasi actually performs, and each is described with what it can and cannot do, its regulatory status, its downtime, and its risks. Nothing is done before the good-faith exam, the medical examination that comes before any aesthetic treatment.
The plan always starts with a conversation about your goals, not with a product. Sometimes the right answer is a better sunscreen and a simpler routine. What regenerative aesthetics really means goes into the term in more depth.
Options map
What PrimeCell offers, and what each option is for
Each tool suits a different problem. Dynamic lines, skin texture, tone and volume loss are different problems, and many people have more than one.
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01
Neurotoxins
PrimeCell uses Botox Cosmetic (onabotulinumtoxinA) and Xeomin (incobotulinumtoxinA, Merz). Both are prescription drugs that temporarily relax selected muscles to soften expression lines. Both are FDA-approved for moderate to severe frown lines, forehead lines and crow’s feet in adults; Botox Cosmetic is also approved for moderate to severe neck (platysma) bands.5,6 Other areas are off-label.
FDA-approved · specific areas Other areas off-label
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02
Hyaluronic-acid fillers
Juvéderm and Restylane are families of hyaluronic-acid gels that add volume or contour on the day, for example in the cheeks, lips or smile lines. Each product is an FDA-approved device for specific areas and ages; use elsewhere is off-label. Hyaluronic acid can be dissolved with an enzyme if needed.4
FDA-approved devices · specific areas Other areas off-label
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03
Collagen stimulators
Radiesse (calcium hydroxylapatite, Merz) and Sculptra (poly-L-lactic acid) prompt your own tissue to build collagen gradually over a series of visits. They suit mild-to-moderate volume loss when you want to look rested rather than filled.
FDA-approved devices · specific areas Other areas off-label
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04
Medical microneedling
A device creates controlled micro-channels in the skin, which prompts a wound-healing and remodeling response. It is used for texture, selected acne scars and fine lines. Randomized trials show objective improvement in acne scars, with moderate-quality evidence.7 Depth, device and aftercare matter more than the name of the facial.
FDA-cleared devices · specific uses
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05
PRP / PRF skin procedures
Platelet-rich plasma or platelet-rich fibrin is prepared from a small draw of your own blood. It can be applied during microneedling or placed with fine injections to support skin quality. This is the evidence-based core of what is often marketed as a “PRF facial.” Evidence for facial rejuvenation is real but limited, drawn mostly from small studies.8
Off-label · physician practice
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06
Stem-cell-derived and exosome therapies
In selected cases, after an evaluation and written informed consent, PrimeCell offers regenerative skin procedures using stem-cell-derived (birth-tissue) or exosome products, alone or with microneedling or PRP. These products are not FDA-approved for any cosmetic use, and the evidence in people is early.1
Investigational · not FDA-approved
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07
Barrier-first, Korean-inspired care
Gentle cleansing, layered hydration, daily sun protection and a routine your skin can tolerate. These are the K-beauty principles that make every procedure work better and hold its result longer.
Skin care · no prescription
Status tags describe U.S. regulatory status for aesthetic use. “Specific areas” means the FDA approval or clearance covers named indications only; the same product used elsewhere on the face is off-label, which is legal and common but should be disclosed to you. “Investigational” means no FDA approval for that use and early evidence. PrimeCell does not offer lasers or chemical peels.
Fillers & collagen stimulators
Fillers add volume. Collagen stimulators build it slowly.
A hyaluronic-acid filler such as Juvéderm or Restylane adds volume on the day. A collagen stimulator such as Radiesse or Sculptra prompts your own tissue to produce collagen over the following weeks and months, so the change is slow, subtle and cumulative.
All four are regulated by the FDA as medical devices, and each product is approved for specific areas and for adults over 21.4 Hyaluronic-acid fillers suit defined contour or lip goals and can be adjusted or dissolved. Radiesse (calcium hydroxylapatite) gives some immediate support plus gradual collagen stimulation. Sculptra (poly-L-lactic acid) gives almost none on the day and builds over a series of sessions spaced several weeks apart.
Collagen stimulators suit people with mild-to-moderate volume loss, for example after weight loss or with age, who want gradual improvement. They do not suit someone who wants sharp contouring before an event; a hyaluronic-acid filler, or nothing, may fit better.
Worth knowing before you choose
Unlike hyaluronic-acid fillers, collagen stimulators cannot be dissolved with an enzyme if you dislike the result. Nodules can appear, sometimes months later. Rarely, any filler can be injected into a blood vessel, which the FDA notes can cause tissue death, vision problems including blindness, or stroke.4 Technique and anatomy matter, and so does the physician. Which product, if any, suits you is decided after your exam.
Sculptra: what to expect and who it fits
Series, timeline and candidacy for poly-L-lactic acid.
Collagen stimulators vs. fillers: the real difference
Mechanism, reversibility and the kind of result each gives.
How long do collagen stimulators really last?
What the durability data show, and what they do not.
Also read: the risks of collagen stimulators.
Stem cells, exosomes & search terms
“Stem cell facials”, exosomes and PRF: what the terms mean, and what PrimeCell does
If you searched for a stem cell facial, an exosome facial or a PRF facial in Orlando, this is the plain-English version: what those names usually describe, what PrimeCell actually does, and what the FDA has and has not approved.
Short answer
A “stem cell facial” rarely involves living stem cells; the name usually describes microneedling with a serum made from plant extracts, cell-culture media or exosomes. PrimeCell offers regenerative aesthetic procedures with PRP/PRF and, in selected cases after written informed consent, stem-cell-derived or exosome products. No stem cell or exosome product is FDA-approved for any cosmetic use.1
- FDA-approved / cleared
The FDA has approved the drug or device, or cleared the device, for a named use. Other uses may be off-label.
- Off-label / physician practice
An approved product, or a device-prepared material from your own body, used in a way the FDA has not specifically reviewed.
- Investigational · not FDA-approved
No FDA approval for this use, and early evidence. The FDA has warned consumers about unapproved products in this group.2
| What you searched | What it usually means | U.S. status | At PrimeCell |
|---|---|---|---|
| “Stem cell facial” | A facial or microneedling with a serum made from plant stem-cell extracts, cell-culture (“conditioned”) media or exosomes. Living human stem cells are rarely involved. | No approved product | Not offered under that name. The options below are described by what they contain |
| Stem-cell-derived skin therapy | A product derived from donated birth tissue, such as umbilical cord tissue, injected or applied to the skin. | Investigational · not FDA-approved | Offered in selected cases, with written informed consent |
| Exosome facial · microneedling with exosomes | Extracellular vesicles from cultured cells, without living cells, applied to freshly microneedled skin or injected. | Investigational · not FDA-approved1 | Offered in selected cases, with written informed consent |
| PRF facial · PRP facial | Your own platelets (PRP) or a fibrin-rich version (PRF), applied during microneedling or by fine injection. | Off-label | Offered after evaluation · details |
| Microneedling with PRP | Medical microneedling with PRP applied to the skin. | Device cleared PRP off-label | Offered after evaluation |
| Polynucleotides · Rejuran · PDRN | Injectables made from purified DNA fragments, typically salmon-derived; widely marketed in Korea. | Not FDA-approved or cleared in the U.S. | Explained here as terminology only |
| Plant “stem cell” skin care | Creams and serums with plant-cell extracts. Plant cells cannot act as human stem cells. | Cosmetic, not approved10 | Discussed as part of home care |
Regenerative aesthetics with PRP, stem cells and exosomes
PrimeCell offers exosome (extracellular-vesicle) and stem-cell-derived products for skin in selected cases, after a physician evaluation and written informed consent. No exosome or stem cell product is FDA-approved for any cosmetic use, and the FDA has issued a public safety notification about unapproved exosome products.1,2 These therapies are investigational, and the evidence in people is early.
The written consent covers the type of product and its source, its regulatory status, what is and is not known, the risks (including infection and immune reactions), the alternatives and the cost. PRP and PRF, made from your own blood, have more published evidence and are usually discussed first.
Microneedling devices are regulated by the FDA as medical devices, and specific devices have been authorized for specific uses, such as the appearance of facial acne scars or facial wrinkles in adults.3 Putting an unapproved biologic on freshly needled skin does not make that biologic approved.
The Florida notice near the top of this page is required because Dr. Chantasi performs stem cell therapies that are not FDA-approved.9 Stem-cell-derived and exosome aesthetic procedures are outside FDA approval and investigational.
Why physician-led
Why a pain and rehabilitation physician practices aesthetics
Dr. Chantasi’s path into aesthetics is personal. It is not a claim about results.
Over about a year, as part of a weight-loss journey that included GLP-1 therapy, he lost roughly 100 pounds. His face and skin changed along with the weight, and he experienced the same questions many of his weight-management patients now ask about volume, laxity and skin quality.
His wife is Korean and has long been passionate about Korean skin care. Her influence shaped his interest in consistency, barrier health and long-term maintenance over aggressive correction. He then completed formal aesthetic certification training.
His day-to-day medical training matters too. Board certification in Physical Medicine & Rehabilitation and Pain Medicine means working every day with anatomy, needle precision, tissue healing and honest conversations about what a procedure can and cannot do. Dr. Chantasi performs PrimeCell’s aesthetic evaluations and treatments himself.
Philosophy
Natural results are a decision, not an accident
Overcorrection usually comes from treating a face area by area. We look at the whole face and plan conservatively. It is easier to add than to undo.
- i.
Skin quality before volume
Texture, tone and barrier health often change how old someone looks more than volume does. We address them first, because they are lower-risk and they make everything else look better.
- ii.
Movement kept, not erased
Neurotoxin dosing is mapped to the way your face moves. The goal is to soften the lines you dislike, not to lose the expressions people recognize as you.
- iii.
Staged, then reviewed
Plans are built in steps with a check-in between them. The PrimeCell Aesthetic Outcomes Follow-Up asks whether the result matched your goals. Its purpose is to find out, not to sell the next visit.
Weight loss & your face
Skin and volume changes after GLP-1 weight loss
Short answer
Losing a significant amount of weight, with or without a GLP-1 medication, can reduce facial fat and make skin look looser or more tired. People sometimes call this “Ozempic face,” but it is not a diagnosis. The medication is not damaging your skin; the change comes from the weight loss itself. Some of it can be supported with skin-quality procedures and gradual collagen stimulation, and the timing matters.
We usually suggest waiting until your weight has stabilized before planning volume-related treatment, because the face keeps changing while you are still losing. Protecting muscle and eating enough protein during weight loss matter for how you look as well as for your health. At PrimeCell the same physician manages both, so the plans can be coordinated rather than competing.
The PrimeCell Aesthetic Goals Assessment
Your goals set the plan, not a package
Every aesthetic consultation starts here. It covers what you want to change and what you want to keep. “Nothing yet” is a valid outcome.
Goals & history
What bothers you, what you want to keep, prior injectables and procedures, medications, allergies and healing history.
Good-faith exam
The medical examination before any treatment: movement at rest and in expression, symmetry, skin quality, pigmentation risk and volume.
Options, honestly compared
What each option can do, its regulatory status, downtime, risks, alternatives and cost. Sometimes the answer is to do less.
Plan & follow-up
A staged plan with a written estimate, then the Aesthetic Outcomes Follow-Up to check the result against your goals.
The PrimeCell Aesthetic Outcomes Follow-Up has no published results yet. Findings will be shared only when enough patients have completed follow-up to report them honestly.
Candidacy
Who is a good fit, and what we will not do
Often a good fit
- Adults who want to look rested and healthy, not different
- Expression lines, dull or uneven skin, texture, or early volume loss
- People changing shape after weight loss who want a coordinated plan
- Anyone who prefers gradual change and a physician’s opinion before a purchase
- Patients willing to protect results with sunscreen and a consistent routine
What PrimeCell will not do
- Show fake, borrowed or AI-generated before-and-after photos
- Overcorrect, or keep treating once the plan’s goal has been reached
- Imply that any stem cell or exosome product is FDA-approved, or use one without written informed consent
- Recommend a procedure during active infection, pregnancy or an unstable skin condition
- Promise a result, a duration, or that you will look a particular age
Downtime & risks
What recovery looks like, and what can go wrong
These are typical ranges. Your own risk depends on your skin, your health history and the exact plan, and it is reviewed with you before any treatment.
| Option | Typical downtime | Common, usually temporary | Less common or serious |
|---|---|---|---|
| Neurotoxins | Little or none; avoid rubbing and strenuous exercise the same day | Pinpoint bruising, tenderness, headache | Eyelid or brow droop, asymmetry. Rarely, spread of toxin effect causing swallowing, speech or breathing difficulty (boxed warning).5,6 |
| Hyaluronic-acid fillers | Swelling and possible bruising for a few days | Swelling, bruising, tenderness, lumps | Rarely, injection into a blood vessel, which can cause tissue damage, vision loss or stroke. Can usually be dissolved with an enzyme.4 |
| Medical microneedling | Redness for about one to three days | Redness, swelling, dryness, flaking, pinpoint bleeding | Infection, cold-sore flare, pigment change, scarring |
| PRP / PRF skin | Similar to microneedling; injections may bruise | Swelling, bruising at procedure and draw sites | Infection; results vary and are not guaranteed |
| Collagen stimulators | Swelling and tenderness for several days | Bruising, temporary lumpiness | Nodules (sometimes months later); rarely, blockage of a blood vessel. Not reversible with an enzyme.4 |
| Stem-cell-derived and exosome products | Similar to microneedling or injection | Redness, swelling, tenderness | Infection, contamination or immune reactions; long-term effects unknown1 |
| Barrier-first skin care | None | Irritation when a new active is started | Allergic or irritant reactions to specific ingredients |
Cost
Self-pay, with the plan and the price in writing
Cosmetic procedures are not covered by insurance, and PrimeCell does not bill insurance. Cost depends on the product, the dose or amount, the areas involved and the number of sessions. After the good-faith exam you receive a written estimate, before anything is done.
Qualifying patients can spread payments with Cherry. PrimeCell members can direct their annual allowance toward eligible aesthetic services, including injectables, collagen stimulation, microneedling and PRP/PRF-based procedures.
Go deeper
Questions patients research before an aesthetic consult
Physician-reviewed, with sources.
- Non-surgical facial rejuvenation that looks natural
- Botox in Orlando: what to know before your first treatment
- How to support collagen production, with and without procedures
- Is Korean skin care safe? What U.S. and Korean rules cover
- How much does Sculptra cost, and what drives the price?
- Who is (and is not) a candidate for exosome products
Also evaluated here
Hair and sexual wellness
Dr. Chantasi also evaluates thinning hair and hair loss and erectile dysfunction. Both start with a medical workup and FDA-approved options; regenerative therapies for them are investigational.
Questions
Regenerative aesthetics FAQ
Does PrimeCell offer stem cell or exosome skin therapies?
Yes, in selected cases, as investigational therapies after a physician evaluation and written informed consent. No stem cell or exosome product is FDA-approved for any cosmetic use. PrimeCell does not sell a generic “stem cell facial”; each procedure is described by what it actually contains.
Are exosome facials FDA-approved?
No. No exosome product is FDA-approved for any medical or cosmetic use, and the FDA has issued a public safety notification about unapproved exosome products. Applying one to microneedled skin does not change that.
What is a PRF facial?
It usually means platelet-rich fibrin, prepared from your own blood, applied during microneedling or with fine injections. It is an off-label, physician-performed procedure. The evidence for PRP in facial rejuvenation is real but limited, based mostly on small studies.
What are Rejuran and polynucleotides?
Rejuran, polynucleotide and PDRN injectables are made from purified DNA fragments and are marketed widely in Korea. They are not FDA-approved or cleared in the U.S. PrimeCell explains them here as terminology; they are not presented as a PrimeCell service.
Which injectables does PrimeCell use?
Botox Cosmetic and Xeomin neurotoxins, Juvéderm and Restylane hyaluronic-acid fillers, and Radiesse and Sculptra collagen stimulators. Whether any of them suits you, and which, is decided after the good-faith exam.
Does PrimeCell offer Dysport, Jeuveau or Daxxify?
No. They are FDA-approved botulinum toxin products, and our journal explains how they compare, but PrimeCell uses Botox Cosmetic and Xeomin.
Will I look “done”?
The plan is designed to avoid that. We work conservatively, keep facial movement, address skin quality before volume and stage treatments with a check-in between them. It is easier to add than to undo.
Can you help with face changes after GLP-1 weight loss?
Often, yes, once your weight is stable. Options may include skin-quality procedures and gradual collagen stimulation. Because Dr. Chantasi also manages medical weight loss, the timing can be coordinated with your weight plan.
Are results guaranteed?
No. Aesthetic outcomes vary between people. PrimeCell does not publish before-and-after photos or outcome statistics until they can be reported honestly.
Look rested. Still look like yourself.
Start with the PrimeCell Aesthetic Goals Assessment with Dr. Chantasi. You get an honest read of your skin, your options and your costs, including when the right answer is to do less.
$97Initial physician consultation · offer valid through October 31, 2026
THE PATIENT AND ANY OTHER PERSON RESPONSIBLE FOR PAYMENT HAS A RIGHT TO REFUSE TO PAY, CANCEL PAYMENT, OR BE REIMBURSED FOR PAYMENT FOR ANY OTHER SERVICE, EXAMINATION, OR TREATMENT THAT IS PERFORMED AS A RESULT OF AND WITHIN 72 HOURS OF RESPONDING TO THE ADVERTISEMENT FOR THE FREE, DISCOUNTED FEE, OR REDUCED FEE SERVICE, EXAMINATION, OR TREATMENT.
References
- U.S. Food and Drug Administration. Public safety notification on exosome products. fda.gov
- U.S. Food and Drug Administration. Consumer alert on regenerative medicine products including stem cells and exosomes. fda.gov
- U.S. Food and Drug Administration. Regulatory considerations for microneedling products (guidance for industry and FDA staff). fda.gov
- U.S. Food and Drug Administration. Dermal fillers (soft tissue fillers), and FDA-approved dermal fillers (list). fda.gov
- BOTOX Cosmetic (onabotulinumtoxinA) prescribing information, including indications and boxed warning. DailyMed, U.S. National Library of Medicine. dailymed.nlm.nih.gov
- XEOMIN (incobotulinumtoxinA) prescribing information, including indications and boxed warning. DailyMed, U.S. National Library of Medicine. dailymed.nlm.nih.gov
- Shen et al. Meta-analysis of 12 randomized trials of microneedling for acne scars. Aesthetic Plast Surg. 2022. doi:10.1007/s00266-022-02845-3
- Xiao et al. Systematic review of platelet-rich plasma for facial rejuvenation. Clin Cosmet Investig Dermatol. 2021. doi:10.2147/CCID.S340434
- Florida Statutes §458.3245 and §459.0127, Stem cell therapy (2025). flsenate.gov
- U.S. Food and Drug Administration. Cosmetics & U.S. law. fda.gov
Medically reviewed by Kenny Chantasi, DO, on September 23, 2026. General education only; not medical advice. Candidacy is determined at an individual evaluation. Stem-cell-derived and exosome products are investigational and not FDA-approved for cosmetic use. Aesthetic outcomes vary and are not guaranteed. BOTOX® Cosmetic, XEOMIN®, JUVÉDERM®, RESTYLANE®, RADIESSE® and SCULPTRA® are registered trademarks of their respective owners; other product names mentioned are trademarks of their respective owners.